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Book Details :
Published on: 1994-01-20
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Original language: English

In line with other volumes in the Neuroscience Perspectives Series, this volume covers the background, pharmacology, molecular biology, and biochemistry of antipsychotic drugs, together with an overview assessment of the therapeutic considerations. Over the past 40 years, the effectiveness of conventional neuroleptic agents for psychotic illness has been offset by a wide range of adverse side-effects, including motor side-effects like parkinsonism. Studies show that lowering doses may still produce the antipsychotic effect while lessening the risk of side-effects. As all available antispychotic drugs are able to block dopamine, specifically D2 receptors, doses below the threshold level for producing acute motor disorder can still be therapeutically effective. With the identification and characterization of multiple dopamine receptors, the possibility of more selective drugs with better side-effect potential has arisen. Other novel antipsychotic agents include D1 receptor blockers, partial dopamine agonists and non-dopamine drugs such as 5-HT receptor blockers, sigma receptor antagonists and NMDA receptor agonists. This volume reviews both the basic science of the conventional and atypical neuroleptics and their present and potential therapeutic use. Drugs their targets and the nature and number of drug ... Top of page Abstract. What is a drug target? And how many such targets are there? Here we consider the nature of drug targets and by classifying known drug ... Co-Occurring Disorders Psychology Today Just as the field of treatment for substance use and mental disorders has evolved to become more precise so too has the terminology used to describe people with both ... Asperger syndrome - Wikipedia Asperger syndrome; Synonyms: Asperger's syndrome Asperger disorder (AD) Asperger's: Restricted interests or repetitive behaviors such as this boy's interest in ... Dopamine - Wikipedia Dopamine exerts its effects by binding to and activating cell surface receptors. In mammals five subtypes of dopamine receptors have been identified labeled from D1 ... Effectiveness of Antipsychotic Drugs in Patients with ... Original Article. Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia. Jeffrey A. Lieberman M.D. T. Scott Stroup M.D. M.P.H. Joseph P ... Schizophrenia - mentalhealth.com Schizophrenia: Irrationality Negative Emotion And Detachment Wisdom vs Irrationality: Continuous cognitive impairment (distractibility apathy forgetfulness ... Cannabinoids in health and disease Cannabis sativa L. preparations such as marijuana hashish and dagga have been used in medicine for millenia. 1 Investigations into the chemistry of Cannabis began ... Information about Mental Illness and the Brain - NIH ... Mental Illness and the Brain 4. The term mental illness clearly indicates that there is a problem with the mind. But is it just the mind in an abstract sense or is ... New Diabetes Drugs In Pipeline - prediabetes weight loss New Diabetes Drugs In Pipeline Treatment Diabetes & Alternative Diabetes Treatment New Diabetes Drugs In Pipeline ::The 3 Step Trick that Reverses Diabetes ... Clozapine-Induced Agranulocytosis -- Incidence and Risk ... Clozapine is an atypical antipsychotic agent that is more effective than standard neuroleptic drugs in the treatment of patients with refractory schizophrenia. Unlike ...
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